RT @TheNutrivore: No problem. High LDL with a low TG/HDL ratio is still inferior to low LDL with a low TG/HDL ratio within the same dataset…
No problem. High LDL with a low TG/HDL ratio is still inferior to low LDL with a low TG/HDL ratio within the same dataset Feldman loves to cite: https://t.co/6g4qFpu8Bj High LDL predicts plaque volume in metabolically healthy populations too: https://t.co
@LDLSkeptic @DietHeartNews Hi David. I came across this study which seems to suggest that LDLc is a risk even for those metabolically healthy. Your thoughts? https://t.co/vsIaTHX1Le
@twitevit @AlastairMcA30 @DrPaulMason That’s incorrect https://t.co/F3INbdgUqX
@ml_easy @DrNadolsky @NutritionMadeS3 @KoushikReddyMD Elevated LDL increases risk of atherosclerosis even in the absence of any other risk factors https://t.co/FwChRn2oTg
@Mespejel29 @Eli23541052 @kevinstock12 “Within normal limits” like these metabolically healthy people? https://t.co/RrPOXsr6Rm https://t.co/ji3G29sLZH
4/10 Even when LDL-C is normal in the context of optimizing other major risk factors, lower LDL-C is still better in a dose-dependent manner. We know the optimal LDL-C range is far, far lower than the "normal" LDL-C range. https://t.co/CwA7gNRDmJ https://
@maxlugavere @BaboonWatch TC/HDL and TG/HDL are correlates for ApoB, which is why they're generally more reliable markers than LDL-C. Your ApoB is likely higher. But, regardless. Your position doesn't fly, based on the PESA results. I'll link it again. ht
@maxlugavere @BaboonWatch You do realize your LDL is higher to degree that is probably clinically relevant, right? https://t.co/CwA7gNRDmJ
LDL-C levels and atherosclerosis from PESA study below https://t.co/txU2OI0nzl https://t.co/Wiu2uBv0Cw
@PeterFaberSP @Tom_Babington1 @NutritionMadeS3 https://t.co/CwA7gNRDmJ https://t.co/6g4qFpu8Bj https://t.co/xMHRw28AHH Get clear on this literature before talking about this subject, k?
@PeterFaberSP @TheCarnivoreKid @realDaveFeldman are you aware atherosclerosis begins in childhood? And people with no risk factors have atherosclerosis in a dose response manner to LDL? https://t.co/4ueOFAbVL0
@AmandaZZ100 @ScepticalDoctor @MacroFour @dylanarmbruste3 @Plant_proof @krosenque @NutritionMadeS3 @deirdre_tobias @realDaveFeldman @MacroEight @MattMadore576 @MyNutritionSci @drmatthewnagra And then you've got the PESA cohort. LDL independently associated
@wyadvd @MacroFour @MichaelAlbertMD @ifixhearts @realDaveFeldman I suppose the closest we have is this from the pesa cohort. We see degree of atherosclerosis track with LDL, independent of other risk factors. https://t.co/qIdbXchyg4 https://t.co/fsqS6Tzd
@MichaelAlbertMD I appreciate the amendment and the intellectual honesty, but I think it's probably still wrong in terms of ASCVD. Not sure about events. I think we could infer that increasing subclinical ASCVD would be likely to increase the risk of event
@Tony87505461 @DiscoStew66 Or maybe there are just multiple causal factors in the development of CVD? But still, LDL is independently associated with the degree of ASCVD, even in those without other risk factors. Probably best to manage all risk factor
@change_states @PeterFaberSP It's also beside the point, because Dave's lipid triad has been investigated multiple times. There's still an increase in risk. https://t.co/CwA7gNRDmJ https://t.co/6g4qFpu8Bj
@jon_alessi @MichaelMindrum @JesseLunsford The ideal LDL is actually less than 100 mg/dL it's more like 50-70 according to this. https://t.co/pkRsQpfsRH Levels currently classified as "normal" are based on the population not ideal levels and are associat
@erreyedoc @MichaelMindrum We do have this showing LDL-C is associated with atherosclerosis progression independent of other cardiovascular risk factors. https://t.co/aX1OGj4rQf https://t.co/cKMvAAvVxS
@RaisinTheStakes @TheeBurgerDude I got something you might like. https://t.co/Z10YzE1oBf https://t.co/HGsb9Qs8kw
@henry77761681 @ifixhearts I still think it's worth managing LDL levels even if other risk factors are in an ideal range. A CAC score may be useful but it's my understanding that a number of CV events occur in individuals with a CAC of 0 (as it doesn't c
@MichaelMindrum Sorry this is the PESA study link I was thinking of that speaks more to LDL-C: https://t.co/OM7kp5lwdn
@kevinnbass @PlantBasedLift1 Particularly given the ave. persons LDL sits at about 125 mg/DL in US (& Aus) placing them at higher risk of atherosclerosis. https://t.co/DnsjbpW5Tv https://t.co/nVXAM4QAfZ
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @JonathanDune: Hogwash... https://t.co/3qcFH9zzqm
Hogwash...
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
RT @NutritionMadeS3: the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of…
the PESA study showed a dose-dependent relationship between LDL-cholesterol level and plaque, *even in the absence of other major risk factors* this is one (of many) reasons LDL-c/LDL/apoB is considered an *independent* CVD risk factor https://t.co/5x1vBR
@LDLSkeptic @GardnerPhD I know you’re familiar with the PESA cohort, and your response is exactly number 1, just hand waving without a valid reason because you don’t want to accept the findings. https://t.co/Oigx3ws31w Clear as day. https://t.co/gPuwLgb4Q
@mosca_matthew @IMWHorvitz @AlexJLeaf @jerryteixeira @raphaels7 @DoctorTro @LDLskeptic2 LDL levels still correlate with subclinical atherosclerosis even in the absence of other cardiovascular risk factors. https://t.co/V6XUnph7i6
@dylanarmbruste3 @SquiggleBK @Drlipid You can try this one https://t.co/ZJ4NvfkIuk
@The_Nutrivore @Tom_Babington1 @POhukainen https://t.co/yfkBUkT5KL Mentioned it here after Tom had already, here's an actual link: https://t.co/NeQaVUNDrJ and this was the response: https://t.co/4GL1mfQpSo
@Adityalch @The_Nutrivore 1. Do you actually read the citations provided? https://t.co/60jrVAzcCo. 2. Can you provide evidence for this?
@Adityalch @The_Nutrivore How do you think atherosclerosis develops in the first place? Look. LDL matters. Even without other risk factors https://t.co/3lD7KgSJ7i https://t.co/WGPJlKyt6f
La aterosclerosis subclínica parece afectar incluso a personas que no presentan factores de riesgo cardiovascular, y con un colesterol LDL menor a 100mg/dl, normalmente tomado como rango saludable. Fuente: https://t.co/nR17pE5zlc https://t.co/4KbTYF33jH
@StolteThiago @KetoCarnivore Looks like after adjustment for BP, BMI, diabetes etc, apoB was still a strong predictor of CAC. In this one, even in the absence of other risk factors, LDL was still associated with atherosclerosis. Confirming its independen
@Gearoidmuar @Alecsplaining "In this study of apparently healthy individuals without conventional CVRFs, we demonstrated a direct, independent link between LDL-C levels and atherosclerotic burden. In fact, LDL-C was the strongest modifiable factor associa
@Jevan @DBelardoMD Traditional cardiovascular risk models clearly underestimate the role of LDL https://t.co/5JyZ3jRw2n
RT @MyNutritionSci: @DaveKeto @ryanvdreyer @Tom_Babington1 And in every context so far, higher LDL increases CVD risk. The causality of LDL…
@DaveKeto @ryanvdreyer @Tom_Babington1 And in every context so far, higher LDL increases CVD risk. The causality of LDL is not dependent on the lipid triad. There is already data of LDL causality in the absence of other risk factors.. a linear relationship
"Normal" LDL-C levels are associated with atherosclerosis https://t.co/txU2OIhqBl https://t.co/qKKAlbHoVe
Kyseessä tutkimus keski-ikäisistä jossa käsiteltiin nimenomaan prekliinisen ateroskleroosin määrää. https://t.co/xqFw8uoDB8 Tämä luku on hyvin linjassa potilaanlääkärilehden kirjoituksen kanssa. Siinä todetaan, että n. puolet suomalaisista saa asiaan liit
RT @drtom_butler: @escardio Some interesting evidence suggest that there is even some risk with "normal" levels and that its not only amoun…
thanks for sharing tom fascinating will take a look at this you an expert in this topic! #rduk
@escardio Some interesting evidence suggest that there is even some risk with "normal" levels and that its not only amount that is important, but also the duration of exposure. See https://t.co/aRm2Y99bxU and https://t.co/rUHACvusQL #rduk #DietAndCholest
RT @AlexJLeaf: Question for the lipid people! Why would a keto person with high LDL and low HDL / TG be protected from atherosclerosis whe…
Because MAGIC KETONES!!!
Question for the lipid people! Why would a keto person with high LDL and low HDL / TG be protected from atherosclerosis when metabolically healthy adults see a linear increase in subclinical atherosclerosis with increasing LDL-C concentrations? https://t
@sh_akers @AntJamesMusic Take a look at the referenced study. The inclusion criteria was metabolically healthy with zero risk factors. This study may meet Dave's inclusion criteria, @The_Nutrivore https://t.co/wRKR2dYiN0
RT @Borjaibanez1: @PesaStudy (CNIC-Banco Santander collab) showed @JACCJournals a linear association btw LDL & atherosclerosis in young in…
RT @Borjaibanez1: @PesaStudy (CNIC-Banco Santander collab) showed @JACCJournals a linear association btw LDL & atherosclerosis in young in…
RT @Borjaibanez1: @PesaStudy (CNIC-Banco Santander collab) showed @JACCJournals a linear association btw LDL & atherosclerosis in young in…
@PesaStudy (CNIC-Banco Santander collab) showed @JACCJournals a linear association btw LDL & atherosclerosis in young individuals (even in the range considered "normal" LDL without additional risk factors! should we reconsider what is "normal" LDL?htt
Mielenkiintoinen tutkimus. Prekliinistä ateroskleroosia löytyy jo suomalaisittainkin suht "normaalit" LDL arvot omaavilta. Suom. LDL keskiarvo n. 3.5 mmol/l (kuvassa 140-150mg/dl) ja heilläkin n. 50% löytyy alkavaa valtimonkovettumatautia. https://t.c
@drericbergdc You are not a real doctor. https://t.co/rICJpxCjN4
And in actual fact we start to see atherosclerosis at LDL levels over 60 https://t.co/ZoF0H7IeKx https://t.co/1x8i44mGgC
@World_Egg_Day Gross....... https://t.co/6gLpMeg1ot
@healthcoachkait LDL: https://t.co/E22XCvNkz4 LDL:https://t.co/cWzguVS3vm LDL:https://t.co/JTQ92JtexM Baseline: https://t.co/unP84MJNRv Optimal: https://t.co/4iVkK8yjhh CVD: https://t.co/ZanvfdORO5 CHD: https://t.co/0xi14INQz0 CVD: https://t.co/Q6WVBhhSYZ
@bryan_trader @foundmyfitness No you don't need LDL for anything. Stop spreading misinformation. People who have the lowest ldl-levels have the lowest amount of subclinical atherosclerosis. 90% of people with LDL levels of 60-70mg/dl develope no subcl. at
@Huge_E87 @drmatthewnagra @BioLayne I'm not sure if you are just dishonest by changing the claim from 70 to 60, or if you're just not tracking the conversation. Your said 70, not 60. Regardless, for LDL levels 60-70mg/dl, 11% had atherosclerosis. https://
@NoahRevoy LDL: https://t.co/E22XCvNkz4 LDL:https://t.co/cWzguVS3vm LDL:https://t.co/JTQ92JtexM Baseline: https://t.co/unP84MJNRv Optimal: https://t.co/4iVkK8yjhh CVD: https://t.co/ZanvfdORO5 CHD: https://t.co/0xi14INQz0 CVD: https://t.co/Q6WVBhhSYZ CVD: h
@GSpoultry1 @mariemamiii Shut up fat ass. https://t.co/MvSUga7u7x
@Dave06031956 Educate. https://t.co/MvSUga7u7x
@Dave06031956 You keep saying that. That means you raised vegan children also yet you talk shit about vegan parents. #Meatheals https://t.co/MvSUga7u7x
@Dave06031956 Fuck that chiropractor. https://t.co/MvSUga7u7x
@chriskresser You were doing ok for a while. #Forestplot https://t.co/MvSUga7u7x
@BluelineKeto @bigfatsurprise Fighting for what?https://t.co/MvSUga7u7x
@LOWCARB_TOOLBOX Do they remind you of science?https://t.co/MvSUga7u7x
@KenDBerryMD Can you read a forest plot?https://t.co/MvSUga7u7x
@drandyphung @FatEmperor @grahamsphillips Woke from what?https://t.co/Yy92IlQj1a
@davidasinclair @Mangan150 Duh..........https://t.co/K8ljydfARI
RT @Plant_proof: Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors | JACC: Journ…
Normal LDL-Cholesterol Levels Are Associated With Subclinical Atherosclerosis in the Absence of Risk Factors | JACC: Journal of the American College of Cardiology That’s right friends 👇🏼 https://t.co/4yBaRgrCU9