RT @AChoiHeart: @RonBlankstein @ErinMichos @JAMACardio @dmljmd @NorthwesternU @CiccaroneCenter @ASPCardio @Heart_SCCT In addition, the data…
RT @AChoiHeart: @RonBlankstein @ErinMichos @JAMACardio @dmljmd @NorthwesternU @CiccaroneCenter @ASPCardio @Heart_SCCT In addition, the data…
RT @AChoiHeart: @RonBlankstein @ErinMichos @JAMACardio @dmljmd @NorthwesternU @CiccaroneCenter @ASPCardio @Heart_SCCT In addition, the data…
@RonBlankstein @ErinMichos @JAMACardio @dmljmd @NorthwesternU @CiccaroneCenter @ASPCardio @Heart_SCCT In addition, the data for cost effectiveness for an #YesCCT approach is consistent across datasets This includes the #CONSERVE pragmatic RCT in #JACCIMG
@mikejohansenmd @VPrasadMDMPH @drjohnm Nope! Especially because you can ignore those too, claim you made your endpoint and still publish in a great journal: https://t.co/0KRnG9Pe2D
RT @venkmurthy: Let's count the high profile CCTA papers with math that doesn't add up! * CONSERVE - CIs cross null hypothesis but still m…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
As a prior reviewer for JACC I rely on the statistical folks to get this level of detail, and get it right. Seems like they missed the boat on this one. If there is a statistical counterpoint I would love to hear it.
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @swatigar: Not my field. But very interesting. Kudos to people who take the trouble to do a detailed analysis of a paper. And yes paper…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
Not my field. But very interesting. Kudos to people who take the trouble to do a detailed analysis of a paper. And yes paper authors should think of responding scientifically.
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @medicalaxioms: I have no idea if Venk’s math is right here but I really appreciate someone taking the “journal club” position that it’s…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @medicalaxioms: I have no idea if Venk’s math is right here but I really appreciate someone taking the “journal club” position that it’s…
I have no idea if Venk’s math is right here but I really appreciate someone taking the “journal club” position that it’s the statistics that are squirrelly, not the enrollment criteria, methods, or some other “hidden bias.”
RT @venkmurthy: Let's count the high profile CCTA papers with math that doesn't add up! * CONSERVE - CIs cross null hypothesis but still m…
RT @venkmurthy: Let's count the high profile CCTA papers with math that doesn't add up! * CONSERVE - CIs cross null hypothesis but still m…
RT @venkmurthy: Let's count the high profile CCTA papers with math that doesn't add up! * CONSERVE - CIs cross null hypothesis but still m…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
Please take the time to read @venkmurthy going through the flawed maths reported by the CONSERVE trial. Outstanding work 👏👏👏, showing once again the misuse of non-inferiority trials
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
@f2harrell @richarddmorey @lakens @statsepi @FaustoBustos @ADAlthousePhD @MaartenvSmeden And perhaps miscalculated too! https://t.co/0KRnG9Pe2D
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @cardiojaydoc02: This is so so good. The devil is in the details. https://t.co/x8sOqJOA6I
This is so so good. The devil is in the details.
Reading threads like this make me a better PT by challenging me to think more critically of the research I read 🤓🤓
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Let's count the high profile CCTA papers with math that doesn't add up! * CONSERVE - CIs cross null hypothesis but still m…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @MKIttlesonMD: I am impressed that @venkmurthy took the extraordinary trouble to parse this out and explain it so clearly. The devil is…
RT @venkmurthy: Coming soon! Part 2: why Intention to Treat is good sometimes but not always (like here) Part 3: what does this say about…
I am impressed that @venkmurthy took the extraordinary trouble to parse this out and explain it so clearly. The devil is in the details!
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Coming soon! Part 2: why Intention to Treat is good sometimes but not always (like here) Part 3: what does this say about…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
Coming soon! Part 2: why Intention to Treat is good sometimes but not always (like here) Part 3: what does this say about sensitivity & specificity of CCTA Read through Part 1 at link below and PLEASE RETWEET!
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
How can 1.47 be LESS than 1.33? Help me figure it out in this tweetorial about the CONSERVE trial! https://t.co/VRG5o3uBmu
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @WestraJelmer: Crystal clear review of non-inferiority trial recently published in @JACCJournals https://t.co/eku4Phurs8
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
Crystal clear review of non-inferiority trial recently published in @JACCJournals
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
@cecilejanssens @MaartenvSmeden @mkeulemans @aliettejonkers Great rules. No point in debunking a paper nobody cares about. I was on fence about CONSERVE because pt estimate is ~1.0 anyway, but I do think its relevant when NI trial uses wide margin, alpha=
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @SoerenLK: Interesting post publication review of a non-inf trial - well done @venkmurthy https://t.co/TfXRzFSJyC
Interesting post publication review of a non-inf trial - well done @venkmurthy
Good points. I would add trials that compare diagnostic strategies become self-fulfilling profecies if set for noninferiority. Because It is hard to obtain differences between diagnostic strategies in major clinical endpoints. There is always a trend to si
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @TariqAzamMD: Great #EBM thread by @venkmurthy - as a mentor in residency used to say ‘while you all are looking at results, I’m looking…
Great #EBM thread by @venkmurthy - as a mentor in residency used to say ‘while you all are looking at results, I’m looking at methods’ #medtwitter
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
RT @jvrbntz: It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is…
It’s rare to find physicians who, for various reasons, openly and validly criticize research studies. Open valid criticism is essential for science and medicine, this is how science works. I keep learning lots from these few physicians and I am very gratef
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
Glad I can relegate my critical thinking to @venkmurthy !
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @cardiotrials: CONSERVE trial: Marked differences were seen in the rates of invasive coronary angiography. Is CONSERVE trial a game-chan…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @ASarkarMD: Resounding self reminder to not take literature at face value. I am thankful to all my mentors who taught me the importance…
Resounding self reminder to not take literature at face value. I am thankful to all my mentors who taught me the importance of trying to understand the data and evaluating which patient the results may apply to. #cardiotwitter
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
Another trial destroyed by careful statistical dissection @venkmurthy 👏 you should report this to editor/@PubPeer ?
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @drjohnm: Legit critique of a trial that could change cardiology. (Referral patterns for Cath is a big deal). Would hope to hear a resp…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…
RT @venkmurthy: Guys, please retweet this. If pt 1 gets a decent audience, will do pt 2 where we see how this prospective RCT shows CCTA h…
RT @venkmurthy: Recently the CONSERVE trial was cited on twitter as supporting use of CCTA b/c it showed that patients sent for ICA could u…