AIによるフェノタイピング Cohen JACC 2020 https://t.co/dbTtyr4oTi ただ、ここで運動負荷等の判断がないので 今後はそっちも重要だぞと!
駆出率が保たれた心不全の臨床表現型:詳細な表現型、予後、およびスピロノラクトンに対する反応 https://t.co/77KHRXaA2G
TXP festa day3より HFpEF患者をクラスタリングして高齢者が集まったフェノタイプはスピロノラクトンで予後改善が得られそう。 このフェノタイプ内ってRCTデータだからexchangebilityやposibility、consistencyが保たれていてATEが得られているということ? https://t.co/R07hUECuLb
HFpEFとは何か。 EFだけでは語れない、深い深いお話なのです。 #心不全道場
HFpEFこそ、異質性の権化。 それぞれ全然違う。 ますます個別化医療... #まだまだ仕事ある #心不全道場 Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction... https://t.co/3dZed76hxB
P2 in elderly HFpEF 🤔 🎈> comorbidity / #frailty ⬆️ inflammaging #cardiogeriatria #CardioTwitter #geriatric @GuillenRosaldo @GeriatricCardio Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction... https://t.co/BbuWTNspcf https://t.co
HFpEFをAIで分けてみた!! #U40 Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction... https://t.co/3dZed7nkzB
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @cladelucia: How many distinct clinical phenogroups of #HFpEF patients exist? Using data from the TOPCAT trial, a Univ. of Colorado team…
RT @cladelucia: How many distinct clinical phenogroups of #HFpEF patients exist? Using data from the TOPCAT trial, a Univ. of Colorado team…
How many distinct clinical phenogroups of #HFpEF patients exist? Using data from the TOPCAT trial, a Univ. of Colorado team identifed groups based on cardiac and arterial structure/function and responses to spironolactone therapy. https://t.co/a0ErPSBD19 #
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @BSHeartFailure: It remains surprising that so many trials have come and gone for "HeFpEF", and we're still not certain what it is!
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @AAlMohammad87: This is a good step in the right direction to understand HFpEF and perhaps to stop considering or treating HFpEF as a si…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
It remains surprising that so many trials have come and gone for "HeFpEF", and we're still not certain what it is!
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
This is a good step in the right direction to understand HFpEF and perhaps to stop considering or treating HFpEF as a single entity. A step in the right direction towards specific therapy to specific sub-type. @JACCJournals DOI: 10.1016/j.jchf.2019.09.009
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JonathanDavisHF: More discussion of #HFpEF phenotypes, such a heterogeneous disease. Perhaps different subtypes more amenable to specif…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @Cardiobro: Phenotype of HFpEF is key on predicting 'responders' to Spironolacrone ✅Obese ✅Renal/hepatic dysfunction ✅Diabetic ✅ 🔼Inflam…
Phenotype of HFpEF is key on predicting 'responders' to Spironolacrone ✅Obese ✅Renal/hepatic dysfunction ✅Diabetic ✅ 🔼Inflammation ✅ 🔼 Renin 🚨 Highest risk cohort
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @AndrewJSauer: Reinforcing @HFpEF original phenomapping from 2015, more #TOPCAT insight. Spiro and metabolic disease. Clinical Phenogrou…
I think it’s about time we got more precise with HFpEF
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
More discussion of #HFpEF phenotypes, such a heterogeneous disease. Perhaps different subtypes more amenable to specific treatments?
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
RT @JACCJournals: How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in bioma…
How many distinct clinical phenogroups of patients with #HFpEF exist? @JulioChirinosMd et al. assess differences in biomarkers, cardiac and vascular features, and responses to spironolactone therapy in TOPCAT patients. https://t.co/XjWKcnKFcQ #JACCHF @yale
Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction https://t.co/V7xzk8Nu0i
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
The authors identified three distinct HFpEF phenogroups, with differences in circulating biomarkers, cardiac/arterial characteristics, prognosis, and response to spironolactone. #heartfailure https://t.co/o2ZafCmBoB
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @CpaolaParedes: Role of metabolic diseases and inflammation burden as a target for MRA. Looking for the right patient @nossikoff @LuizaA…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
Role of metabolic diseases and inflammation burden as a target for MRA. Looking for the right patient @nossikoff @LuizaAguilera @LilitBaghdasar3
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @Office_j: 【HFpEFに3つの表現型?:TOPCAT追加解析/ JACC HF】 1)若年、喫煙癖多、心血管基質的異常小、2)高齢、AF合併、CV気質的異常、自己免疫マーカー高値 [?]、3)肥満、CKD、高レニン、TNF-α高値——。2,3で死亡率高。スピ…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone - PubMed Phenotype 3( DM, obesity and etc) showed a favorable response to Spironolactone🤩 https://t.co/f7pB6cptOl
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @Office_j: 【HFpEFに3つの表現型?:TOPCAT追加解析/ JACC HF】 1)若年、喫煙癖多、心血管基質的異常小、2)高齢、AF合併、CV気質的異常、自己免疫マーカー高値 [?]、3)肥満、CKD、高レニン、TNF-α高値——。2,3で死亡率高。スピ…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @AnastasiaSMihai: Congratulations @jordy_bc & coauthors for yr @JACCJournals & teasing impt data from TOPCAT trial 👏👏 Importance of Cli…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
RT @CousiratLiendro: Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección…
Análisis exploratorio del #TOPCAT. Fenotipos clínicos de pacientes con insuficiencia cardíaca con fracción de eyección conservada: pronóstico y respuesta a la espironolactona. #HFpEF #heartfailure #IC #cardiotwitter https://t.co/RioJ8vn5xk
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
RT @hvanspall: This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fib…
This exploratory cluster analysis of the #TOPCAT trial ID’d 3 phenotypes in #HFpEF; group w/ AF, CKD, obesity, DM, liver fibrosis, inflammatory markers had the highest risk of CV death, HF hospitalization, aborted cardiac arrest @AndreasGevaert https://t