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American College of Cardiology

Article Metrics

Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques

Overview of attention for article published in JACC: Basic to Translational Science, December 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 201)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

news
53 news outlets
blogs
1 blog
twitter
19 tweeters
facebook
3 Facebook pages

Readers on

mendeley
3 Mendeley
Title
Percutaneous Sampling of Local Biomolecule Gradients Across Coronary Artery Atherosclerotic Plaques
Published in
JACC: Basic to Translational Science, December 2017
DOI 10.1016/j.jacbts.2017.07.007
Pubmed ID
Authors

Nick E.J. West, Joseph P. Corrigan, Richard H.G. Owen, Stephen P. Hoole, Adam J. Brown, Stephen Blatcher, Andrew C. Newby

Abstract

A percutaneous catheter device, the Liquid Biopsy System, was developed to sample the unstirred boundary layer of blood upstream and downstream of intact and disrupted human coronary atherosclerotic plaques. Using multiplexed proximity extension assays, release of 20 biomolecules was simultaneously detected in samples taken across plaques before balloon angioplasty, including the soluble form of the endothelial lectin-like oxidized LDL receptor. Additional biomolecules, including matrix metalloproteinase-12, were released after plaque disruption with angioplasty. These experiments demonstrate the power of the Liquid Biopsy System to yield new scientific insights and its ultimate potential to generate new biomarkers and surrogate endpoints for clinical trials.

Twitter Demographics

The data shown below were collected from the profiles of 19 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Other 1 33%
Student > Ph. D. Student 1 33%
Student > Doctoral Student 1 33%
Readers by discipline Count As %
Medicine and Dentistry 2 67%
Agricultural and Biological Sciences 1 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 431. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2018.
All research outputs
#17,941
of 12,109,122 outputs
Outputs from JACC: Basic to Translational Science
#1
of 201 outputs
Outputs of similar age
#1,120
of 333,585 outputs
Outputs of similar age from JACC: Basic to Translational Science
#1
of 12 outputs
Altmetric has tracked 12,109,122 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 201 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,585 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.