| Title |
Antihyperglycemic Therapies to Treat Patients With Heart Failure and Diabetes Mellitus
|
|---|---|
| Published in |
JACC: Heart Failure, August 2018
|
| DOI | 10.1016/j.jchf.2018.05.020 |
| Pubmed ID | |
| Authors |
Abhinav Sharma, Lauren B. Cooper, Mona Fiuzat, Robert J. Mentz, João Pedro Ferreira, Javed Butler, David Fitchett, Alan Charles Moses, Christopher O’Connor, Faiez Zannad |
| Abstract |
There is increasing recognition of the relationship between diabetes and heart failure (HF). Comorbid diabetes is associated with worse outcomes in patients with HF, and death from HF forms a large burden of mortality among patients with diabetes and atherosclerotic cardiovascular disease. However, there is evidence of harm relating to the risk of HF outcomes from several antihyperglycemic therapies. The absence of well-powered randomized controlled studies has resulted in significant treatment variations in the glycemic management in patients with coexisting diabetes and HF. However, there is emerging evidence from recent clinical trials suggesting that sodium-glucose-co-transporter-2 inhibitors may be used as a therapy to improve HF outcomes. In order to understand the current state of knowledge, we reviewed the evolving evidence of antihyperglycemic therapies and present strategies to optimize these therapies in patients with diabetes and HF. This analysis is based on discussions among scientists, clinical trialists, industry sponsors, and regulatory representatives who attended the 12th Global Cardiovascular Clinical Trialists Forum, Washington DC, December 1 to 3, 2016. |
X Demographics
The data shown below were collected from the profiles of 139 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 33 | 24% |
| United States | 11 | 8% |
| Colombia | 11 | 8% |
| Mexico | 9 | 6% |
| Argentina | 4 | 3% |
| United Kingdom | 2 | 1% |
| Canada | 2 | 1% |
| Chile | 2 | 1% |
| Venezuela, Bolivarian Republic of | 2 | 1% |
| Other | 8 | 6% |
| Unknown | 55 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 100 | 72% |
| Practitioners (doctors, other healthcare professionals) | 24 | 17% |
| Scientists | 10 | 7% |
| Science communicators (journalists, bloggers, editors) | 5 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 72 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 14% |
| Researcher | 7 | 10% |
| Student > Bachelor | 7 | 10% |
| Other | 6 | 8% |
| Student > Ph. D. Student | 6 | 8% |
| Other | 9 | 13% |
| Unknown | 27 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 33% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
| Nursing and Health Professions | 5 | 7% |
| Agricultural and Biological Sciences | 1 | 1% |
| Computer Science | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 35 | 49% |
Attention Score in Context
This research output has an Altmetric Attention Score of 74. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2019.
All research outputs
#584,121
of 25,728,855 outputs
Outputs from JACC: Heart Failure
#155
of 1,624 outputs
Outputs of similar age
#12,314
of 341,972 outputs
Outputs of similar age from JACC: Heart Failure
#6
of 29 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,624 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,972 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.