@DrSiyabMD 98% of premature CVD patients look nothing like this person. Have you looked at data? 61 is past premature. Here's FH vs nonFH 45 y/o MIs. Overweight/T2D/IR/smoking/HTN overwhelmingly common. https://t.co/lTUXcwvmyf https://t.co/NJdpPJasyS
This study had 23% w/ DM, and 39% with obesity, not typical of FH. But in current era, FH pts, likely everyone else, are affected by obesity and metabolic syndrome, so they can have high TGs and more small dense LDL than patients with normal BMI.
@Lpa_Doc Has this changed? b/c this recent early MI (avg age 45) comparing FH to non-FH data argues otherwise. probable IR/MetS criteria is higher in this FH group. Do we need to distinguish athero itself from cvd events in the context of lipoprotein patte
@shivadas29 @ethanjweiss @KCKlatt @DrNadolsky Or here. Also young MIs and FH. No shortage. See table 1. High rates of overweight, diabetes, hypertension, smoking, MetS. These cohorts of MIs are incredibly unhealthy irrespective of their FH status. And
RT @VietHeartPA: @VivekKulkarniMD @DrMarthaGulati @cardiojaydoc02 Love the infographic from @TheFHFoundation and this paper: https://t.co/E…
@VivekKulkarniMD @DrMarthaGulati @cardiojaydoc02 Love the infographic from @TheFHFoundation and this paper: https://t.co/E0qFLfi3Dp @cpcannon @DLBHATTMD @AvinainderSingh - Young MI 3/ https://t.co/kpk4w0i4ef
These and other #YoungMI studies were led by: @AvinainderSingh @ersied727 @davidwbiery @SanjayDivakaran https://t.co/mZSQxIWgLx https://t.co/VZ4xSY09v0 https://t.co/axhxvZ9Wl8
Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/xqSRdUnsqG https://t.co/qeqd3TyIcP
@AviBittMD @The_Nutrivore I have no interest in the infection theory. But from this study of young HeFH MIs, their HDL is low or lower, their Trigs, obesity, T2D, smoking rates are as high or higher than non-FH patients. Very few are single risk factor c
@The_Nutrivore @thoroughlyconf1 https://t.co/8mAehEg05T In this paper, where FH is responsible for 1/10 premature cardiac events, 50% of FH patients smoke, 40% are obese, 60% have HTN. Still not single RF patients.
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
Nice summary @krychtiukmd #JACC Look for signs of #AVS common in individuals with #FH and high #Lp_a #FHWeek #FHAwareness
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
RT @krychtiukmd: It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/…
It is #FHweek! - 1/10 young (<50yrs) MI patients have FH - 2/10 with family history - 4/10 with FH and LDL > 160mg/dL - 6/10 with family history and LDL > 160mg/dL #knowFH #findFH @JACCJournals @fhscglobal https://t.co/FTNXYazPm8 https://t.co/Z
@ZKForTre What changed? https://t.co/D6NnWkDg89 Also note the high rates of OW/Obesity/T2D/HTN/IR lipids and smoking in young probable-FH MIs. https://t.co/ehZH2pntRR https://t.co/pA4DGCjNzT
RT @WeiserTom: Q9 this research intrigues me because of the age factor #KnowFH https://t.co/AK2qsNF2ku
Q9 this research intrigues me because of the age factor #KnowFH https://t.co/AK2qsNF2ku
RT @VietHeartPA: System approach targeting #FH assessment to younger pts presenting w/#STEMI has higher yield for dx. While late(er) for pt…
System approach targeting #FH assessment to younger pts presenting w/#STEMI has higher yield for dx. While late(er) for pt, can target cascade screening to their families. #knowFH @TheFHFoundation @JACCJournals @Intermountain https://t.co/eOSX8dam17 @DLBHA
@ninehigh99 @FatEmperor @POhukainen Isn't the issue that in a highly overweight population FH and OW/Obesity/IR overlap? Examples: First a study of FH MIs, IR metrics were more common in the FH group. Second, relation between abdominal fat, IR and CVD in
@skathire @mbelshazly @ErikIngelsson @ethanjweiss @aidanbutty @amitvkhera Fits this young MI study as well. Under age 50, FH and non-FH. The connection between low HDL / high trigs and abdominal obesity on a mixed diet is pretty settled. https://t.co/jGi
Familial Hypercholesterolemia Among Young Adults < 50y-o, With Myocardial Infarction. 11th Year Death Rate: 11%! @JPUsdin. Rate 11% https://t.co/dAISN1tCOD
RT @braun_lynne: Up to 1/3 of young adults with FH and MI are not discharged on high intensity statin. @TheFHFoundation #FindFH @lipiddoc @…
L,B key
RT @ATRIUMRx: YOUNG-MI registry: ONLY 43% of patients, < 50 years old, with familial hypercholesterolemia achieve > 50% reduction in LDL-c…
YOUNG-MI registry: ONLY 43% of patients, < 50 years old, with familial hypercholesterolemia achieve > 50% reduction in LDL-c one year post-myocardial infarction #weneedtodobetter #LDLcheck #statins https://t.co/fExDbciTPr https://t.co/VZXoyA1kJl
RT @braun_lynne: Up to 1/3 of young adults with FH and MI are not discharged on high intensity statin. @TheFHFoundation #FindFH @lipiddoc @…
RT @braun_lynne: Up to 1/3 of young adults with FH and MI are not discharged on high intensity statin. @TheFHFoundation #FindFH @lipiddoc @…
RT @braun_lynne: Up to 1/3 of young adults with FH and MI are not discharged on high intensity statin. @TheFHFoundation #FindFH @lipiddoc @…
Up to 1/3 of young adults with FH and MI are not discharged on high intensity statin. @TheFHFoundation #FindFH @lipiddoc @avolgman @gina_lundberg Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/1ltxDiwgJD
Familial Hypercholesterolemia Among Young Adults With MI - Almost 10% of patients aged ≤50 with type 1 MIs had FH in a disease registry, but few achieved target LDL levels 1 year later. https://t.co/FKXrGpZTiw
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @JACCJournals: What is the prevalence of clinically-defined familial hypercholesterolemia and the rates of statin utilization and LDL ch…
RT @JACCJournals: What is the prevalence of clinically-defined familial hypercholesterolemia and the rates of statin utilization and LDL ch…
What is the prevalence of clinically-defined familial hypercholesterolemia and the rates of statin utilization and LDL cholesterol achieved 1-year post #cvMI? https://t.co/JiTcw3vA3H #JACC https://t.co/KEAOGc9m1z
RT @jacabreracardio: 🔹Need for more aggressive lipid-lowering therapy in young patients post-MI 🔹@JACCJournals @esthermerinola https://t.co…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
国内でもほぼ同等の報告あり。 なによりFHは子供や孫世代をACSから救う(しかも予防する)ことができるという意味で診断価値は高い。
RT @Office_j: 【若年発症MIの10例に1人はFH?/ JACC】 米国、振り返りコホート、50歳以下MI発症1996例解析:9%がProbable/definiteなFH。うち42.9%は発症前にスタチン非服用。 https://t.co/BY5y3pHTFq…
【若年発症MIの10例に1人はFH?/ JACC】 米国、振り返りコホート、50歳以下MI発症1996例解析:9%がProbable/definiteなFH。うち42.9%は発症前にスタチン非服用。 https://t.co/BY5y3pHTFq https://t.co/OO8swolpfK
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
@kevinnbass Is anyone arguing that FH doesn't exist? Also IR increases TC / LDL-c and decreases hdl. Nuance is lost in your post when u ignore hdl, BP and smoking while the underlying study analyzed all the above. And note: https://t.co/uBVQmG0VIT
RT @jacabreracardio: 🔹Need for more aggressive lipid-lowering therapy in young patients post-MI 🔹@JACCJournals @esthermerinola https://t.co…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction. https://t.co/nR7c4ZcjXS
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @jacabreracardio: 🔹Need for more aggressive lipid-lowering therapy in young patients post-MI 🔹@JACCJournals @esthermerinola https://t.co…
🔹Need for more aggressive lipid-lowering therapy in young patients post-MI 🔹@JACCJournals @esthermerinola
Simply cannot ignore hereditary dyslipidemias. Elevated LDL-c is NOT ok.
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @iamritu: https://t.co/JjvHNYvDBu #YOUNG-MI registry ~2k pts median age 45 yo -10% of #STEMI prob/definite FH (180 pts) -43% were not 🚫o…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
.@NIH_NHLBI supported study shows that clinically defined FH was present in nearly 1 of 10 patients with MI at a young age. Only 63% of FH patients were discharged on high-intensity #statin therapy, and the vast majority had elevated LDL at 1 year. #KnowFH
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
RT @JACCJournals: #JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of…
#JACC study finds familial hypercholesterolemia (FH) was present in 1 in 10 patients w/ #cvMI at a young age. Only 2/3 of FH patients were discharged on high intensity statin, & the vast majority had elevated LDL-C at 1 year. https://t.co/TJTOOUyXuj ht
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @DLBHATTMD: Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/gcFYQ98odk
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
RT @JACCJournals: Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9%…
Analysis of nearly 2,000 young patients with myocardial infarction found familial hypercholesterolemia was present in 9% of patients and high-intensity statins were prescribed in only 49%. https://t.co/UBETEHllWE #JACC #cvMI https://t.co/8FXCDVBIk0
@lansberg @RChrisCC Irony? This recent FH MI study demonstrates what FH and IR have in common: it's IR. https://t.co/jGiHfm7WzB
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/V9wpPEfONA
RT @kalrasadi: Prevalence, management, and outcomes of familial hypercholesterolemia in patients with acute coronary syndromes in the Arabi…
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
Awesome paper congrats @khurramn1 @RonBlankstein and team ! #knowFH
RT @khurramn1: #1 Great report by @AvinainderSingh @RonBlankstein on High prevalence of clinically defined FH phenotype in young presenting…
RT @DLBHATTMD: Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/gcFYQ98odk
RT @DLBHATTMD: Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction https://t.co/gcFYQ98odk
@mrc314 @FatEmperor @gerdosi @PeterFaberSP @bokkiedog @DaveKeto @DrDavidKatz @TheSohoForum @bigfatsurprise Timely young (45 and under) MI study: Approx 2000 Heart Attacks, including 180 suspected FH patients: Avg HDL 36. Avg Trigs approx 150. Obesity,