Meta-analysis of patients with atrial fibrillation on long-term dialysis in 16 observational studies showed no reduction in thromboembolism for those receiving oral anticoagulation but did show more bleeding. RCTs needed. @JACCJournals @SripalBangalore htt
5mg BID of apixaban had similar efficacy to rivaroxaban, warfarin and dabigitran in preventing thromboembolism and also had less bleeding - according to this analysis may have the best overall safety / efficacy profile in ESRD pts with #AFIB | JACC https:/
RT @gonzaeperez: ANTICOAGULACIÓN ORAL EN #AFib Y HEMODIALISIS Metanálisis 16 estudios observacionales ✔️No beneficio en embolia ni stroke c…
【メタ分析】AFの長期HD患者への経口抗凝固薬(OAC)(OACなしと比べてApixabanとWarfarinは脳卒中and/or全身性血栓塞栓症減少と関連しなかった。Apixaban5mgは死亡率低下と関連した。Warfarin、DabigatranとRivaroxabanはApixabanやOACなしと比べて大出血リスク増加と関連した。 https://t.co/6rOHnOWYMe
RT @DebbeMcCall: No benefit of OAC in #AFib with #CKD on #hemodialysis, except Apixaban 5mg, bid, not apixaban 2.5 mg bid. #stroke
RT @DebbeMcCall: No benefit of OAC in #AFib with #CKD on #hemodialysis, except Apixaban 5mg, bid, not apixaban 2.5 mg bid. #stroke
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @Yuki_Sahashi: 心房細動を有する透析患者の抗凝固薬のメタ解析 from JACC. Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis |…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
今日のジャーナルクラブはこれだったんだけど、内容よりもなによりも、authorがDr. Kuno. 羨ましくて羨ましくて、心が平穏でない。
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
RT @DebbeMcCall: No benefit of OAC in #AFib with #CKD on #hemodialysis, except Apixaban 5mg, bid, not apixaban 2.5 mg bid. #stroke
No benefit of OAC in #AFib with #CKD on #hemodialysis, except Apixaban 5mg, bid, not apixaban 2.5 mg bid. #stroke
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
RT @cpgale3: This meta-analysis of observational studies (ie no RCTs) showed that OACs were not associated with a reduced risk of thromboem…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
RT @adnanalkhouli: What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospec…
What should we do 4stroke prevention in dialysis patient w NVAF? This MA suggests no benefit to OAC. Attempts to prospectively study OAC or LAAO in this population were halted due 2inability to enroll @drpaulfriedman @guroledip @DJ_Lakkireddy @SamiAlasfar
Agree, a common & difficult scenario! Although only observational studies here, and only 2/16 that included DOACs, it’s at least confirmation that apixaban is safer and assoc with lower mortality? Need RCT! @UMiamiStroke
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @drgokhanaksel: Meta-analiz: 16 çalışma 71877 hasta. HD+AF hastalarında kullanılan OAK’lar, OAK kullanmayan hastalara göre teomboemboli…
RT @drgokhanaksel: Meta-analiz: 16 çalışma 71877 hasta. HD+AF hastalarında kullanılan OAK’lar, OAK kullanmayan hastalara göre teomboemboli…
RT @bernardowise: A meta-analysis of 16 studies, consisting of >70K patients showed NOACs were not associated with a reduced risk of thromb…
Meta-analiz: 16 çalışma 71877 hasta. HD+AF hastalarında kullanılan OAK’lar, OAK kullanmayan hastalara göre teomboembolik olay (stroke vs) gelişimini önlemede etkili bulunmamış! Furthermore, warfarin, dabigatran, rivaroxaban, daha çok kanatmış. RKÇ şart!
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @pavel_olivera: Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis - ScienceDirect https://t.co/g3MDCR…
Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis - ScienceDirect https://t.co/g3MDCRarwg
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @NealSParikhMD: A common and vexing clinical situation: choosing anticoagulant for patients with #stroke/TIA, #afib, and on #dialysis..…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @GT_Trombo: Anticoagulación de la fibrilación auricular en pacientes en diálisis https://t.co/To664eLBim
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
A common and vexing clinical situation: choosing anticoagulant for patients with #stroke/TIA, #afib, and on #dialysis.. A helpful meta-analysis in @JACCJournals https://t.co/j9FJLZq0Zi Though I must admit that, even after reading this, don't know the
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @bernardowise: A meta-analysis of 16 studies, consisting of >70K patients showed NOACs were not associated with a reduced risk of thromb…
A meta-analysis of 16 studies, consisting of >70K patients showed NOACs were not associated with a reduced risk of thromboembolism in #AFib patients on chronic dialysis. #EPeeps https://t.co/snxE247w6Q
RT @ihtanboga: Meta-analyses of obs. studies (include also PS studies) provide "NOTHING" without covariate adjustment and tx*covariate inte…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @TRassafMD: Moving forward...important paper! https://t.co/qWCCypTSuL
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @GT_Trombo: Anticoagulación de la fibrilación auricular en pacientes en diálisis https://t.co/To664eLBim
RT @ihtanboga: Meta-analyses of obs. studies (include also PS studies) provide "NOTHING" without covariate adjustment and tx*covariate inte…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @GT_Trombo: Anticoagulación de la fibrilación auricular en pacientes en diálisis https://t.co/To664eLBim
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Hemodialysis - It May not protect against stroke https://t.co/mgFWolwVdp
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
Anticoagulación de la fibrilación auricular en pacientes en diálisis https://t.co/To664eLBim
Despite its observational component, I think this is a pretty good network meta-analysis with interesting findings.
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @ihtanboga: Meta-analyses of obs. studies (include also PS studies) provide "NOTHING" without covariate adjustment and tx*covariate inte…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
Moving forward...important paper!
Meta-analyses of obs. studies (include also PS studies) provide "NOTHING" without covariate adjustment and tx*covariate interaction(only possible with IPD). cc:@djc795
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
RT @JACCJournals: Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a r…
Meta-analysis of 16 eligible observational studies, consisting of >70K patients showed NOACs were not associated with a reduced risk of thromboembolism in #AFib patients on chronic dialysis. https://t.co/uUpAF3sF9J #JACC https://t.co/BomH6OIMM9
Agreed, the jury is still out there on A. Fib + ESRD and AC but need a prospective trial...since most of this is registries and studies
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
RT @JACCJournals: In patients with #AFib on dialysis, oral anticoagulatants, warfarin, dabigatran, and rivaroxaban were associated with sig…
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…
RT @guroledip: If you want your hemodialysis patient to have a 31.5% “chance” of having a major or clinically relevant bleed over just the…
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…
RT @gonzaeperez: ANTICOAGULACIÓN ORAL EN #AFib Y HEMODIALISIS Metanálisis 16 estudios observacionales ✔️No beneficio en embolia ni stroke c…
RT @guroledip: If you want your hemodialysis patient to have a 31.5% “chance” of having a major or clinically relevant bleed over just the…
RT @gonzaeperez: ANTICOAGULACIÓN ORAL EN #AFib Y HEMODIALISIS Metanálisis 16 estudios observacionales ✔️No beneficio en embolia ni stroke c…
So what do you do when a hemodialysis patient with CHA2DS2-VASC >1 comes to you with Afib? https://t.co/FF39q1ISHU
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
If you want your hemodialysis patient to have a 31.5% “chance” of having a major or clinically relevant bleed over just the first year, yes start him/her on long-term anticoagulant 🤔 Otherwise consider risk factor control (incl sleep apnea, alcohol, ...) +
RT @Angiologist: My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2D…
My patient is on DIALYSIS but also has ATRIAL FIBRILLATION. Should I offer anticoagulation?* *Don't ask me what the CHA2DS2-VASC is. I am making a different point https://t.co/GHApghUoNE @JACCJournals ($) @GBarnesMD https://t.co/Wuug1i6MwS
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…
RT @JACCJournals: Do you know how safe and effective OACs are in #AFib patients on chronic dialysis? New meta-analysis from #JACC provides…