RT @HanCardiomd: Well-conducted #RCTs have repeatedly contradicted practices supported by common sense and clinical observation Common sen…
RT @HanCardiomd: Well-conducted #RCTs have repeatedly contradicted practices supported by common sense and clinical observation Common sen…
RT @HanCardiomd: Well-conducted #RCTs have repeatedly contradicted practices supported by common sense and clinical observation Common sen…
Well-conducted #RCTs have repeatedly contradicted practices supported by common sense and clinical observation Common sense and clinical observation fail b/c of the inability to fully understand complex biopsychosocial systems https://t.co/AjbOBUlQV1 @ACF
RT @DavidLBrownMD: Timely! From @jaccjournals https://t.co/vnOVNtxwgB
Timely! From @jaccjournals https://t.co/vnOVNtxwgB
A excellent review in @JACCJournals that summarizes examples of how common sense or observational findings need to be evaluated rigorously to minimize bias @ACFanaroff @DLBHATTMD @califf001 https://t.co/qyhfSHSSpc
RT @Retlouping: Randomized Trials Versus Common Sense and Clinical Observation https://t.co/y96egMe9ZD https://t.co/jj080ueTzt
Randomized Trials Versus Common Sense and Clinical Observation https://t.co/y96egMe9ZD https://t.co/jj080ueTzt
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
RT @AdamMeakins: Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.…
Why you can NOT rely on common sense and observation in clinic to decide or gage what or how something ‘works’! https://t.co/sImQpUX45j
RT @AdamMeakins: There are many criticisms of RCTs in physio recently! However they remain the best method to understand causal relationshi…
RT @AdamMeakins: There are many criticisms of RCTs in physio recently! However they remain the best method to understand causal relationshi…
RT @AdamMeakins: There are many criticisms of RCTs in physio recently! However they remain the best method to understand causal relationshi…
There are many criticisms of RCTs in physio recently! However they remain the best method to understand causal relationships between interventions and outcomes, and there are many examples of RCTs overturning decades of ‘clinical wisdom’ and observation! h
Your common sense of “what works” and Uninvestigated observations probably don’t mean much. Especially when the starting point is something shown to have little benefits already scientifically https://t.co/B5ZgV9jSjz
RT @dcfpress: @LHatesYouALot https://t.co/Qf8SDYDj7a I comment on Brazilian MD Renato D Lopes...but look who else was involved in this (Goo…
@LHatesYouALot https://t.co/Qf8SDYDj7a I comment on Brazilian MD Renato D Lopes...but look who else was involved in this (Google). The other article was corrected as well. NEJM is complicit to the eyeballs in this. Lancet. NO TRUST. https://t.co/3lbdE7vkmp
RT @das_seed: Several evidences when intuition, common sense analysis failed when well-designed RCT trials are conducted. 1. https://t.co/…
RT @das_seed: Sanofi is indicted for manslaughter over epilepsy drug Depakine as on August 03. Sanofi is accused of revealing risk of drug…
-ve (negative) results against very assumption/logic on which working of plasma therapy is based? Observational studies are too weak compared to limited setting RCTs. Observational studies aren't any evidence, they can only be counted as suggestion. \8
👉Truncation due to death should be handled differently depending on whether a patient- or resource-focused perspective is taken; for the former, a composite approach should be used, while for the latter, a while-alive approach is preferred. \3 https://t.c
RT @das_seed: Sanofi is indicted for manslaughter over epilepsy drug Depakine as on August 03. Sanofi is accused of revealing risk of drug…
Randomized Trials Versus Common Sense and Clinical Observation: JACC R... https://t.co/X5o6uRFCmu Como o senso comum e os estudos observacionais erram? Na maioria das vezes confundindo marcador de risco com alvo causal. RCTs ainda são a melhor solução #C
@drabbyphilips Several evidences when intuitive analysis failed when well-designed RCT trials are conducted. 1. https://t.co/LZajkxz6Wt 2. 22 cases where Phases 2 & 3 had divergent results (sample size & removal of bias matters) @US_FDA (2017) htt
@rashlessdoctor @prat1112001 @das_seed @malini_aisola @RemaNagarajan @shilpajn @d_s_thakur @Students4BE @ArenaClinical @DrRodRohrich Bhushan, also chk out 'Randomized Trials Versus Common Sense and Clinical Observation' via @ACFanaroff et al https://t.co/O
RT @joarhalvorsen: «(...) over the past 4 decades, results from well-done RCTs have repeatedly contradicted practices supported by common s…
RT @joarhalvorsen: «(...) over the past 4 decades, results from well-done RCTs have repeatedly contradicted practices supported by common s…
RT @joarhalvorsen: «(...) over the past 4 decades, results from well-done RCTs have repeatedly contradicted practices supported by common s…
«(...) over the past 4 decades, results from well-done RCTs have repeatedly contradicted practices supported by common sense and clinical observation.» https://t.co/ICBFolgWS1 h/t @pash22
@load_dependent @ThinkActTank @AlexJohnLondon Yup, I agree Lars, u have probably seen this recent article already 'Randomized Trials Versus Common Sense and Clinical Observation' https://t.co/FAIau4tjxo via @ACFanaroff et al
observational or intervention case studies. There are enough evidences that show results in Phase II and Phase III can be contradictory. Efficacy of drug is established by well-blinded RCT. Open-label isn't blinded and this trial was not even https:/
RT @zigorMM: Sobre cómo el sentido común (la lógica) y la evidencia empírica (observación) fallan a la hora de ponerse de acuerdo con la ev…
RT @zigorMM: Sobre cómo el sentido común (la lógica) y la evidencia empírica (observación) fallan a la hora de ponerse de acuerdo con la ev…
RT @zigorMM: Sobre cómo el sentido común (la lógica) y la evidencia empírica (observación) fallan a la hora de ponerse de acuerdo con la ev…
Sobre cómo el sentido común (la lógica) y la evidencia empírica (observación) fallan a la hora de ponerse de acuerdo con la evidencia experimental. El artículo es un aluvión de ejemplos de los 3 mecanismos principales https://t.co/2gYqLuNnw5 https://t.co/4
RT @ACFanaroff: New in @JACCJournals from me and an all-star crew: Randomized Trials Versus Common Sense and Clinical Observation. https://…
@pavannair @prat1112001 @pash22 @AnantBhan @carlos_chaccour @MelissaLDavey @d_s_thakur @GorwayGlobal @giridar100 @CDSCO_INDIA_INF @PriyankaPulla @htTweets @ICMRDELHI @MoHFW_INDIA @ProfBhargava To add further, here's why evidence is necessary. It is human l
RT @das_seed: Sanofi is indicted for manslaughter over epilepsy drug Depakine as on August 03. Sanofi is accused of revealing risk of drug…
RT @das_seed: Sanofi is indicted for manslaughter over epilepsy drug Depakine as on August 03. Sanofi is accused of revealing risk of drug…
Sanofi is indicted for manslaughter over epilepsy drug Depakine as on August 03. Sanofi is accused of revealing risk of drug to pregnant women. BUT, SEC & DCGI didn't think Sanofi needed to conduct large clinical trial for dengue vaccine in 2016/17. \
@bamardis @DrRajivsankar Randomized Trials Versus Common Sense and Clinical Observation https://t.co/7I8Nt2usga
RT @ACFanaroff: New in @JACCJournals from me and an all-star crew: Randomized Trials Versus Common Sense and Clinical Observation. https://…
【総説】無作為化試験対常識と臨床観察(全文フリー) #ペ読 https://t.co/VvPBqeVP0U
Randomized Trials Versus Common Sense and Clinical Observation: JACC R... https://t.co/RCwXMh41Dg
@SeemaAhuja1, @Bioconlimited 👇 may clarify miconception about "opinion" on #Itolizumab #COVID19 funded by @BioconBiologics w/ authors affiliated or getting fund/grants from BIOCON. (PS: Article has MISTAKES, e.g., https://t.co/o4QPlVn6P3 ) Also see: htt
@bryanalafu @DIVIZIO1 Et est-ce une bonne chose ? Qu'en pensez-vous ? Voici une synthèse justement sur les problèmes et les dangers des études observationnelles versus les essais cliniques randomisés. On a fait beaucoup de bêtises à cause des études obs. h
Several evidences when intuition, common sense analysis failed when well-designed RCT trials are conducted. 1. https://t.co/LZajkxz6Wt 2. 22 cases where Phases 2 & 3 had divergent results (sample size & removal of bias matters) @US_FDA (2017) htt
RT @das_seed: @fayedsouza @AskDrShashank @giridar100 @prat1112001 @pash22 @malini_aisola @d_s_thakur @dawalelo Well, this is exactly why we…
@fayedsouza @AskDrShashank @giridar100 @prat1112001 @pash22 @malini_aisola @d_s_thakur @dawalelo Well, this is exactly why we need proper Phase II trial to study dose & safety of drug and Phase III trial to study efficacy of drug. For #Itolizumab, we m
Several evidences where intuition, common sense analysis failed when real-evidence based tests are conducted (well-designed RCT). https://t.co/yt33LYQVKs 22 cases where Phases 2 & 3 had divergent results @US_FDA (2017) https://t.co/eVDUuoWIoq https:
RT @JACCJournals: Should RCTs trump common sense and observation? Can we bring RCTs into the real world? Drs. @ACFanaroff, @RenatoDLopes1,…
Randomized Trials Versus Common Sense and Clinical Observation https://t.co/9TttFEoH3r
RT @MattStockPhD: Society seems quick to point out the flaws in highly controlled research. Some push-back seems appropriate. Viewed throug…
@YazedAlruthia خلال الشهر الماضي نزل أكثر من بحث تتحدث عن نفس الموضوع https://t.co/EQEvx7xsep https://t.co/vWhpVcycxQ
RT @MattStockPhD: Society seems quick to point out the flaws in highly controlled research. Some push-back seems appropriate. Viewed throug…
Society seems quick to point out the flaws in highly controlled research. Some push-back seems appropriate. Viewed through a cardiology lens... “Well-conducted RCTs have repeatedly contradicted practices supported by common sense and clinical observation.”
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
RCT should be always guided by common sense and does not prevail..a title of a #COVID19 era @JACCJournals @PCRonline @EuroInterventio #EAPCI
RT @pash22: Randomized Trials Versus Common Sense & Clinical Observation https://t.co/FAIau4tjxo via @ACFanaroff et al. IMO, @CDSCO_INDIA_I…
RT @MercadalJordi: Sinceramente aun no lo he leido, pero cambiaria el "vs" por "plus" common sense, observation, phisiology and all interpr…
Randomized Trials Versus Common Sense and Clinical Observation https://t.co/9PyKkkWf2c
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
This is a great slide for any clinician.
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
RT @pash22: Randomized Trials Versus Common Sense & Clinical Observation https://t.co/FAIau4tjxo via @ACFanaroff et al. IMO, @CDSCO_INDIA_I…
RT @pash22: Randomized Trials Versus Common Sense & Clinical Observation https://t.co/FAIau4tjxo via @ACFanaroff et al. IMO, @CDSCO_INDIA_I…
RT @pash22: Randomized Trials Versus Common Sense & Clinical Observation https://t.co/FAIau4tjxo via @ACFanaroff et al. IMO, @CDSCO_INDIA_I…
RT @pash22: Randomized Trials Versus Common Sense & Clinical Observation https://t.co/FAIau4tjxo via @ACFanaroff et al. IMO, @CDSCO_INDIA_I…
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
Randomized Trials Versus Common Sense and Clinical Observation: JACC Review Topic of the Week. https://t.co/iS3ldChr3Z
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
Sinceramente aun no lo he leido, pero cambiaria el "vs" por "plus" common sense, observation, phisiology and all interpreted in a pragmatic clinical way!
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
Evidence based medicine vs common sense: tales from the neverending story!
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…
RT @ibnsky: Ensayo clinico aleatorizado no es patente de corso. Seguimos teniendo que usar la cabeza y ser críticos. No creas todo lo que t…
RT @JACCJournals: Randomized trials vs. common sense and observation, which prevails? Learn more in #JACC: https://t.co/IR0Rc6iKE7 @ACFanar…